发明名称 Substituted thiophene carboxylic amide glucagon receptor antagonists, preparation and therapeutic uses
摘要 The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
申请公布号 US7807702(B2) 申请公布日期 2010.10.05
申请号 US20060094406 申请日期 2006.11.21
申请人 ELI LILLY AND COMPANY 发明人 CHAPPELL MARK DONALD;CONNER SCOTT EUGENE;HIPSKIND PHILIP-ARTHUR;TRIPP ALLIE EDWARD;ZHU GUOXIN
分类号 A61K31/41;C07D257/04 主分类号 A61K31/41
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