发明名称 Spiroheterocyclic compounds and their uses as therapeutic agents
摘要 This invention is directed to spiroheterocyclic compounds of formula (I) wherein k, j, p, Q, R1, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed.
申请公布号 US7799798(B2) 申请公布日期 2010.09.21
申请号 US20060402200 申请日期 2006.04.11
申请人 XENON PHARMACEUTICALS INC. 发明人 CHAFEEV MIKHAIL;CHOWDHURY SULTAN;FRASER ROBERT;FU JIANMIN;KAMBOJ RAJENDER;LIU SHIFENG;SEID BAGHERZADEH MEHRAN;SUN JIANYU;SVIRIDOV SERGUEI
分类号 A61K31/437;C07D491/22 主分类号 A61K31/437
代理机构 代理人
主权项
地址