PURPOSE: An envelope for direct mail having layout maximize the advertisement efficiency is provided to enhance the advertisement effect of direct mail and to reduce the consumption cost to a direct mail largely and to also create direct mail agency business, thereby having effect of reducing the returning cost of the direct mail in each company. CONSTITUTION: An envelope for direct mail having layout maximize the advertisement efficiency has sending address(1) and a receiving address(2) on front side, and enclosed the advertisement flyer(3) inside. The direct mail sending envelope encloses the advertisement flyer about a plurality of company inside. The direct mail sending envelope has a layout which a coupon provided by each company is printed with index which proprietary name about each company is written in order in front center side.