发明名称 |
ASPIRIN-TRIGGERED LIPID MEDIATOR |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a compound which can be used for treating or preventing an arterial inflammation, arthritis, or cardiovascular disease; and to provide a treating method by the compound. <P>SOLUTION: The compounds are as follows: 15-hydroxy eicosapentaenoic acid; 18-hydroxy eicosapentaenoic acid; 5, 12, 18-hydroxy eicosapentaenoic acid; and a compound of the formula, wherein R and P may be hydrogen. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
申请公布号 |
JP2010248213(A) |
申请公布日期 |
2010.11.04 |
申请号 |
JP20100134989 |
申请日期 |
2010.06.14 |
申请人 |
BRIGHAM & WOMENS HOSPITAL INC |
发明人 |
SERHAN CHARLES N;CLISH CLARY B |
分类号 |
A61K31/616;C07C59/01;A61K31/202;A61P1/00;A61P7/02;A61P9/00;A61P9/10;A61P9/14;A61P11/00;A61P11/06;A61P17/02;A61P17/04;A61P17/06;A61P17/08;A61P19/02;A61P27/02;A61P29/00;A61P37/08;A61P43/00;C07C59/105;C07C59/42;C07C59/58;C07C69/732 |
主分类号 |
A61K31/616 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|