Pharmaceutical forms comprising vardenafil with improved pharmacokinetic properties

摘要

Disclosed is a drug formulation comprising vardenafil in the form of a salt with an acid or vardenafil with an acid, and sugar alcohols, which disintegrates rapidly in the mouth and is characterized in that at least 80% of the vardenafil dose in the substance form employed dissolves at 25°C in 10 ml of physiological saline and the rate of release from the drug formulation in 900 ml of physiological saline within the first 5 minutes in the USP pedal stirrer apparatus at 50 rotations per minute at 37°C is at least 70%.