发明名称 METHOD FOR PERFORMING PROGNOSIS FOR HIGH-RISK BREAST CANCER PATIENTS USING TOP2A GENE ABERRATIONS
摘要 A first exemplary method for performing a prognosis for a breast cancer patient, comprises the steps of determining the status of an aberration of the TOP2A gene in a tissue sample taken from the patient; and estimating the probability of either recurrence-free survival or of overall survival of the patient at a later time based upon a pre determined Hazard Ratio corresponding to the determined status. A second such exemplary method comprises the steps of determining the status of an aberration of the TOP2A gene in a tissue sample taken from the patient; and estimating the probability of either recurrence-free survival or of overall survival of the patient at a later time based upon a pre-determined Kaplan-Meier plot corresponding to the determined status.
申请公布号 US2011027777(A1) 申请公布日期 2011.02.03
申请号 US20070293631 申请日期 2007.03.30
申请人 DAKO DENMARK 发明人 JOERGENSEN JAN TROEST;EJLERTSEN BENT;MOURIDSEN HENNING;NIELSEN KIRSTEN VANG
分类号 C12Q1/68 主分类号 C12Q1/68
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