Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics

摘要

Disclosed herein are 5-pyridazinyla-1-azabicyclo[3.2.1]octane compounds having general formula (I) wherein the substituents are as defined within the spec; in the form of a base or an acid addition salt, as well as in the form of a hydrate or solvate. Also disclosed are methods of preparing said compounds, medicaments, pharmaceutical compositions comprising said compounds and to the use thereof in therapeutics. Said compounds/medicaments/compositions are useful in the treatment and prevention of cognitive impairments; cerebral strokes; prevention of symptoms due to tobacco withdrawal, alcohol withdrawal; treatment of pain; treatment of inflammatory processes.