发明名称 |
Optimizing Expression of Active Botulinum Toxin Type E |
摘要 |
Nucleic acid molecules that comprise modified open reading frames providing increased expression of the encoded active BoNT/E in a heterologous cell, expression constructs and cells comprising such nucleic acid molecules and methods useful for expressing the encoding active BoNT/E from such nucleic acid molecules, expression constructs and cells.
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申请公布号 |
US2011111483(A1) |
申请公布日期 |
2011.05.12 |
申请号 |
US20100904983 |
申请日期 |
2010.10.14 |
申请人 |
ALLERGAN, INC. |
发明人 |
STEWARD LANCE E.;GILMORE MARCELLA A.;FERNANDEZ-SALAS ESTER G.;LI SHENGWEN;MILLER RONALD G.;AOKI KEI ROGER |
分类号 |
C12N1/21;C12N15/31;C12N15/70 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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