| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to biotechnology. Immunogenic composition is described comprising an effective amount of a combination of at least two different proteins or their immunogenic fragments selected from at least two groups of proteins or immunogenic fragments selected from the following groups: group (a): at least one staphylococcal protein binding an extracellular component, or its immunogenic fragment; group (b): at least one staphylococcal transport protein or its immunogenic fragment; group (c): at least one staphylococcal regulator of virulence, toxin or its immunogenic fragment, wherein at least one protein or an immunogenic fragment is selected from the group (a), and at least one protein or immunogenic fragment is selected from the group (b). A vaccine against staphylococcal infection is proposed, which comprises an effective amount of the immunogenic composition described. Also the method to obtain the vaccine is offered. ^ EFFECT: method for preventing or treating staphylococcal infection is proposed, comprising the introduction of the proposed vaccine, as well as method of producing immunoglobulin, comprising the steps of immunisation of the recipient by the proposed vaccine. ^ 17 cl, 7 dwg, 8 tbl, 8 ex |
