| 摘要 |
PROBLEM TO BE SOLVED: To solve such a problem that guiding of a nano-spray ionization capillary tip to a target position such as a cell in the microscopic visual field with only the visual field of a minute region is a process most requiring labor, time and techniques, and becomes a bottleneck in a method for measurement when a sample of the minute region such as one living cell is sucked and captured with the nano-spray ionization capillary tip while carrying out microscopic observation to perform direct mass spectroscopy. SOLUTION: The sample capturing capillary such as the nano-spray ionization capillary tip for piercing the cell etc., under a microscope is held at the end of a robot, and the tip position of the tip thereof is detected and corrected to correct the space coordinates of the tip position of the tip for each tip mounting. Furthermore, a focus plane position for observing the coordinates for the space of a focal position under the microscope is corrected with Z-axis encoding of a microscopic stage to guide the tip between both the points with the robot. Thereby, the sample capturing capillary is guided to the object minute sample such as the cell at a high speed with high accuracy. COPYRIGHT: (C)2011,JPO&INPIT
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