| 摘要 |
PROBLEM TO BE SOLVED: To provide new methods for producing substituted benzimidazole compounds, such as 2-bromo-5,6-dichlorobenzimidazole, which are useful in the production of compounds having antiviral activity. SOLUTION: There are provided methods for producing compounds represented by formula (I), which methods comprise a step of cyclizing 4,5-dichloro-O-phenylenediamine with carbonyldiimidazole and a step of reacting with PO(X)<SB>3</SB>. Wherein, X is halogen. COPYRIGHT: (C)2011,JPO&INPIT
|
