发明名称 Azetidines as MEK inhibitors for the treatment of proliferative diseases
摘要 <p>Disclosed herein are azetidine-amide derivatives of formula I wherein the substituents are as defined within the specification, compositions comprising said compounds, use of compounds in the manufacture of a medicament for inhibiting MEK (MAPK/ERK Kinsase) which are useful in the treatment of proliferative diseases such as cancer.</p>
申请公布号 NZ567140(A) 申请公布日期 2011.09.30
申请号 NZ20060567140 申请日期 2006.10.05
申请人 EXELIXIS, INC. 发明人 AAY, NAING;ANAND, NEEL KUMAR;BOWLES, OWEN JOSEPH;BUSSENIUS, JOERG;COSTANZO, SIMONA;CURTIS, JEFFRY KIMO;DUBENKO, LARISA;JOSHI, ANAGHA ABHIJIT;KENNEDY, ABIGAIL R;KIM, ANGIE INYOUNG;KOLTUN, ELENA;MANALO, JEAN-CLAIRE LIMUN;PETO, CSABA J;RICE, KENNETH D;TSANG, TSZE H;DEFINA, STEVEN CHARLES;BLAZEY, CHARLES M
分类号 C07D409/06;C07D205/04;C07D205/06;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D471/04 主分类号 C07D409/06
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