发明名称 |
Methods for use in human-adapting monoclonal antibodies |
摘要 |
Methods useful for human adapting non-human monoclonal antibodies are disclosed. The methods select candidate human antibody framework sequences from a human germline framework database. |
申请公布号 |
US8093068(B2) |
申请公布日期 |
2012.01.10 |
申请号 |
US20070924094 |
申请日期 |
2007.10.25 |
申请人 |
CHEN SHIZHONG;ZHAO SHANRONG;CENTOCOR, INC. |
发明人 |
CHEN SHIZHONG;ZHAO SHANRONG |
分类号 |
G01N33/536;C07K16/00;G01N33/531 |
主分类号 |
G01N33/536 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|