METHOD OF COMBINATION TREATMENT OF LOCALLY ADVANCED RECTAL CANCER

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely oncology, and aims at combination treatment of locally advanced rectal cancer. It involves radiation therapy with underlying introduction of capecitabine 825 mg/m2 times a day on the radiation days. The treatment is two-staged: the fist stage involves gamma-ray teletherapy in a standard fractionation mode at single basic dose 2.0 Gy for 5 days a week to total basic dose 40.0 Gy. At the second stage, the interval of 14 days is followed by 5 sessions of intracavitary gamma-ray therapy at single basic dose 3.0 Gy to total basic dose 16 isoGy. ^ EFFECT: method provides higher clinical effectiveness in locally advanced rectal cancer ensured by higher radiation dose directly covering the tumour and reduced radiation dose on healthy organs and tissues. ^ 2 ex