METHOD FOR PREDICTION OF RISK OF DELAYED DYSKINESIA ACCOMPANYING NEUROLEPTIC THERAPY IN SCHIZOPHRENICS

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, more specifically to psychiatry, and may be used for prediction of the risk of delayed dyskinesia accompanying schizophrenia treatment. Schizophrenic's blood serum is examined to determine the following biological values: pre-treatment amount and relation of reduced and oxidised glutathiones. The low amount of reduced glutathione (108 mcg/ml) and the reduced to oxidised glutathione ratio index lower than 0.49 provides predicting the high risk of delayed dyskinesia in schizophrenics with underlying neuroleptic therapy. ^ EFFECT: method provides the pre-treatment prediction of the risk of delayed dyskinesia that enables choosing an individual therapeutic approach. ^ 1 tbl, 2 ex