发明名称 |
CORTISTATIN ANALOGUES AND SYNTHESES THEROF |
摘要 |
The present invention relates to analogs of cortistatin A, J, K, and L, having the general formula: I and salts thereof, wherein R1, R2, R3, R4, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin A, J, K, and L, and analogs thereof. |
申请公布号 |
EP2334686(A4) |
申请公布日期 |
2012.05.02 |
申请号 |
EP20090810384 |
申请日期 |
2009.08.28 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
FLYER, ALEC, NATHANSON;LEE, HONG, MYUNG;MYERS, ANDREW, G.;NIETO-OBERHUBER, CRISTINA, MONTSERRAT;SHAIR, MATTHEW, D.;SI, CHONG |
分类号 |
C07D493/08;A61K31/34;A61P35/00;C07D493/02 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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