| 发明名称 |
PYRIDYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION |
| 摘要 |
This invention relates to thiazole I and its therapeutic and prophylactic uses, wherein the variables Rz, Q, J, R1, R3, R5, and R6 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis. |
| 申请公布号 |
US2012129843(A1) |
申请公布日期 |
2012.05.24 |
| 申请号 |
US201113297412 |
申请日期 |
2011.11.16 |
| 申请人 |
ZHANG YAN;TOUNGE BRETT ANDREW;WANG AIHUA;HAWKINS MICHAEL;LEONARD KRISTI ANNE;BARBAY JOSEPH KENT;MAHAROOF UMAR S.M. |
发明人 |
ZHANG YAN;TOUNGE BRETT ANDREW;WANG AIHUA;HAWKINS MICHAEL;LEONARD KRISTI ANNE;BARBAY JOSEPH KENT;MAHAROOF UMAR S.M. |
| 分类号 |
A61K31/4439;A61K31/496;A61K31/5377;A61K31/551;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P19/02;A61P19/04;A61P25/00;A61P25/06;A61P29/00;A61P35/00;C07D417/04;C07D417/14 |
主分类号 |
A61K31/4439 |
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