| 摘要 |
The present invention provides biomarkers for diagnosing depression. Specifically, using one or more compounds selected from the group consisting of ADP-RIBOSE, ATP, ADP, AMP, serotonin, tryptophan, kynurenine, SDMA(symmetricdimethylarginine), threonine, glyceric acid, serine, N-acetylaspartic acid, glutamic acid, trigonelline, creatine, 2-methyl serine, sphingosine, homovanillic acid, piperidine, sulfoxidated methionine, pipecolic acid, sphinganine, ³-butyrobetaine, guanidoacetic acid, isobutyric acid, creatinine, sarcosine, 3-methyl butyric acid, nicotinamide, betaine, ornithine, carnitine, ethanolamine, phosphoethanolamine, taurine, hypotaurine, aspartic acid, methionine, tyrosine, phosphorylcholine, arginine, asparagine, 3-aminobutyric acid, ²-alanine, phenylalanine, lysine, phosphocreatine, alanine, uric acid, choline, isocitric acid, leucine, malic acid, aminoadipic acid, tyramine, valine, glucaric acid, histidine, ADMA (asymmetric dimethylarginine), isoleucine, hydroxyproline and cystathionine as a biomarker for diagnosis, a content of the biomarker in a collected blood sample is measured to diagnose depression. |
