| 摘要 |
PURPOSE: A composition containing HIHP-2 for neuroprotection is provided to treat brain tissue injury and neurologic injury and to suppress microglia activation. CONSTITUTION: A pharmaceutical composition for preventing and treating ischemic brain diseases contains HIHP-2(HMGB1 inhibitory heptamer peptide-2) as an active ingredient. The HIHP-2 has an amino acid sequence of sequence number 1. The ischemic diseases are stroke, cerebral hemorrhage, cerebral infarction, head injury, Alzheimer, vascular dementia, Creutzfeldt-Jakob disease, or coma. A health food for preventing and treating ischemic brain diseases contains HIHP-2 as an active ingredient. The composition is manufactured in the form of powder, granule, tablet, capsule, soft capsule, suspension, emulsion, syrup, oral formulation of aerosol, external use formulation, suppository, and sterilized injection solution.
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