发明名称 Pharmaceutical compounds
摘要 Nonane and decane diazabicyclic derivatives having homopiperazine as main ring, having affinity for the opioidergic μ and/or δ and/or k receptors and/or for all their receptorial subclasses, with central and/or peripheral activity, having formula (I), the isomeric forms and their mixtures included, wherein one or more atoms are in the corresponding isotopic forms: wherein: n is an integer equal to 1 or 2; one of the substituents R and R1 of the nitrogen atoms of the diazabicyclic ring is a —C(O)—RB group, wherein RB is a C1-C10 alkyl group, linear or branched when possible, the other remained substituent of R and R1 has the meanings reported in the description.
申请公布号 US8399457(B2) 申请公布日期 2013.03.19
申请号 US20090512818 申请日期 2009.07.30
申请人 LAZZARI PAOLO;LORIGA GIOVANNI;RUIU STEFANIA;MANCA ILARIA;PANI LUCA;PINNA GERARD AIME;NEUROSCIENZE PHARMANESS S.C. A.R.L. 发明人 LAZZARI PAOLO;LORIGA GIOVANNI;RUIU STEFANIA;MANCA ILARIA;PANI LUCA;PINNA GERARD AIME
分类号 A61P21/02;A61K31/551;C07D487/08 主分类号 A61P21/02
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