<p>A method and a device for performing ultrasonic imaging on an interested region. The method comprises: emitting a first ultrasonic pulse and receiving a first ultrasonic echo signal; emitting a second ultrasonic pulse and receiving a second ultrasonic echo signal; emitting a third ultrasonic pulse and receiving a third ultrasonic echo signal; extracting echo signal components from the first ultrasonic echo signal, the second ultrasonic echo signal and the third ultrasonic echo signal; and producing an ultrasonic image of the interested region according to the echo signal components; wherein, amplitude weight of the third ultrasonic pulse is equal to the sum of amplitude weights of the first ultrasonic pulse and the second ultrasonic pulse in magnitude. The method processes and modulates the plurality of ultrasonic echo signals, so as to separate even nonlinear component and asymmetric component of odd nonlinear component from linear component and symmetric component of the odd nonlinear component in the ultrasonic echo signals, and extract the asymmetric component of the odd nonlinear component and/or the even nonlinear component from the ultrasonic echo signals conveniently.</p>