发明名称 |
USES OF INTERLEUKIN-22(IL-22) IN TREATING AND PREVENTING NERVE DAMAGE DISEASES OR NEURODEGENERATIVE DISEASES |
摘要 |
<p>Disclosed in the present invention are uses of Interleukin-22(IL-22) in treating and preventing nerve damage diseases or neurodegenerative diseases. In particular, disclosed in the present invention are the following uses of IL-22 or IL-22 dimers: (1) protecting neurons to recover damaged nerve functions after ischemic neurological damage in an animal; (2) capable of inhibiting losses of nigra dopaminergic neurons significantly to improve functions of the dopaminergic neurons and reduce the apoptosis of neuron cells in the hippocampus area, thus treating the neurodegenerative diseases.</p> |
申请公布号 |
WO2013097748(A1) |
申请公布日期 |
2013.07.04 |
申请号 |
WO2012CN87694 |
申请日期 |
2012.12.27 |
申请人 |
GENERON (SHANGHAI) CORPORATION LTD. |
发明人 |
WU, DONGDONG;HUANG, ZHIHUA;LIU, HENG;HUANG, YULIANG;YAN, XIAOQIANG |
分类号 |
A61K38/20;A61P25/00;A61P25/14;A61P25/16;A61P25/28 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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