发明名称 |
TREATMENT OF DISEASES BY EPIGENETIC REGULATION |
摘要 |
The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.
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申请公布号 |
US2013281397(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
US201313832484 |
申请日期 |
2013.03.15 |
申请人 |
MCLURE KEVIN G.;YOUNG PETER RONALD;RVX THERAPEUTICS INC. |
发明人 |
MCLURE KEVIN G.;YOUNG PETER RONALD |
分类号 |
A61K31/472;A61K31/4375;A61K31/496;A61K31/517;A61K31/519;A61K31/5377;A61K31/5415;A61K31/695;A61K45/06 |
主分类号 |
A61K31/472 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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