发明名称 |
BETA-AMYLOID-DIRECTED MULTITARGET COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
摘要 |
The compounds of formula (I), or its pharmaceutically acceptable salts, or any stereoisomer or mixture thereof, wherein: R1 is a (C1-C2) alkyl radical; R2 and R3 are radicals independently selected from the group consisting of F, CI and methyl R4 is H or OH; A is a birradical selected from the group consisting of -(CH2)n- and -(CH2)-phenyl-(CH2)-; t is an integer from 0 to 1; and n is an integer from 8 to 15, are useful for the treatment of Alzheimer's disease. |
申请公布号 |
WO2013167711(A1) |
申请公布日期 |
2013.11.14 |
申请号 |
WO2013EP59683 |
申请日期 |
2013.05.09 |
申请人 |
UNIVERSITAT DE BARCELONA;PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE |
发明人 |
MUNOZ-TORRERO LOPEZ-IBARRA, DIEGO;INESTROSA CANTIN, NIBALDO, MANUEL;VIAYNA GAZA, ELISABET;SOLA LAO, IRENE;VAZQUEZ CRUZ, SANTIAGO |
分类号 |
C07D221/18 |
主分类号 |
C07D221/18 |
代理机构 |
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代理人 |
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地址 |
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