发明名称 |
Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol |
摘要 |
The present invention provides an improved process for the synthesis of nebivolol or its pharmaceutically acceptable salts, more particularly hydrochloride salt of formula (I). The present invention further provides a new Form T1 of nebivolol and its pharmaceutically acceptable salts. The present invention also provides pharmaceutical compositions and process for the preparation of a solid oral dosage form of nebivolol hydrochloride of formula (I), without the use of wetting agent, and optionally using binder and/or disintegrant. |
申请公布号 |
US8604222(B2) |
申请公布日期 |
2013.12.10 |
申请号 |
US20050658979 |
申请日期 |
2005.08.01 |
申请人 |
SHETH RAKESH;ATTANTI SRINIVASARAO VEERAVENKATA;PATEL HASMUKH MATHURBHAI;GUPTA VINODKUMAR;NADKARNI SUNIL SADANAND;FOREST LABORATORIES HOLDINGS LIMITED |
发明人 |
SHETH RAKESH;ATTANTI SRINIVASARAO VEERAVENKATA;PATEL HASMUKH MATHURBHAI;GUPTA VINODKUMAR;NADKARNI SUNIL SADANAND |
分类号 |
C07D311/00;A61K31/35 |
主分类号 |
C07D311/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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