发明名称 |
Clostridium chauvoei polypeptide, DNA encoding the polypeptide and a vaccine comprising the polypeptide |
摘要 |
The present invention pertains to the identification and initial characterization of CctA, a novel, secreted toxin of Clostridium chauvoei that represents the major cytotoxic activity of C. chauvoei. This toxin confers C. chauvoei its characteristic strong hemolytic activity towards erythrocytes of various species, since anti-CctA antibodies fully neutralize hemolysis by C. chauvoei on standard blood-agar medium or in cell-free supernatants of liquid cultures. |
申请公布号 |
US8709437(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US201013145882 |
申请日期 |
2010.01.28 |
申请人 |
REDHEAD KEITH;FREY JOACHIM;VILEI EDY M.;ROHWER ANDREAS WALTER CLAUDIUS;JOHANSSON ANDERS;INTERVET INTERNATIONAL B.V.;UNIVERSITAT BERN |
发明人 |
REDHEAD KEITH;FREY JOACHIM;VILEI EDY M.;ROHWER ANDREAS WALTER CLAUDIUS;JOHANSSON ANDERS |
分类号 |
A61K39/08;C07K14/33;C07K16/12;G01N33/566 |
主分类号 |
A61K39/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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