TRANSFORMED CAENORHABDITIS ELEGANS AND METHOD FOR SCREENING FOR SUBSTANCES REGULATING GLUCOSE METABOLISM USING SAME

摘要

The present invention relates to a method for preparing a transformed Caenorhabditis elegans ( C. elegans ) which reacts to glucose by exhibiting fluorescence, and to a method for screening for a candidate substance and for a novel gene capable of regulating glucose metabolism and metabolic diseases using the transformed Caenorhabditis elegans. The transformed Caenorhabditis elegans of the present invention is prepared such that changes in glucose may be easily observed on a real-time basis using a fluorescent microscope. The transformed Caenorhabditis elegans of the present invention enables substances for regulating glucose metabolism to be quickly and accurately discovered, and further, may be expected to significantly contribute to studies on a variety of incurable metabolism-related diseases such as obesity, diabetes, and the like.