| 发明名称 |
FORMULATIONS FOR PARENTERAL DELIVERY OF COMPOUNDS AND USES THEREOF |
| 摘要 |
The present invention provides formulations that achieve effective delivery of methylnaltrexone compositions. The provided formulations are useful for preventing, treating delaying, diminishing or reducing the severity of side effects resulting from use of analgesic opioids. |
| 申请公布号 |
US2015025100(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201314105805 |
申请日期 |
2013.12.13 |
| 申请人 |
Progenics Pharmaceuticals, Inc. |
发明人 |
Shah Syed M.;Ofslager Christian;Fawzi Mahdi B.;Bazhina Nataliya |
| 分类号 |
A61K31/485;A61K47/18 |
主分类号 |
A61K31/485 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising an effective amount of methylnaltrexone or a pharmaceutically acceptable salt thereof, calcium ethylenediaminetriacetic acid (EDTA) or a calcium salt EDTA derivative, and glycine in an aqueous solution, wherein the solution has a pH of about 3 to 4. |
| 地址 |
Tarrytown NY US |
