| 发明名称 |
SMALL MOLECULE COMPOUNDS TO TREAT HEARING LOSS |
| 摘要 |
The invention is directed, in part, to compositions comprising small molecule compounds to treat or prevent hearing loss. Compositions of the present invention also promote sensory hair cell regeneration. Particular compositions comprise ellipticine derivatives, and optionally one or more small molecules that increase Atoh1 expression or activity, and optionally one or more growth factors. |
| 申请公布号 |
US2015025096(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201314380669 |
申请日期 |
2013.02.22 |
| 申请人 |
FATE THERAPEUTICS, INC. |
发明人 |
Thies Robert Scott;Farouz Francine;Wang Zhiyong;Lu Chin-Chun Jean |
| 分类号 |
A61K31/475;A61K9/00;A61K31/506 |
主分类号 |
A61K31/475 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for promoting sensory hair cell regeneration comprising administering to a subject, a composition comprising an ellipticine derivative in an amount effective to increase sensory hair cells in the subject, thereby promoting sensory hair cell regeneration in the subject. |
| 地址 |
SAN DIEGO CA US |
