摘要 |
<p>The present invention relates to a composition for controlling fertility of sperm, containing Nutlin-3a and a pharmaceutical composition for contraceptive, containing Nutlin-3a. According to the present invention, the composition for controlling fertility of sperm, containing Nutlin-3a reduces mobility of sperm, ATP generation, capacitation, expression of UQCRC2 and tyrosine phosphorylation protein, and embryonic development, thereby easily controlling fertility of sperm. Also, the pharmaceutical composition for contraceptive, containing Nutlin-3a mass-produces a large number of contraceptive pills.</p> |