| 发明名称 |
HAIR FOLLICLE STEM CELLS AND METHODS OF USE SAME |
| 摘要 |
The disclosure provides isolated hair follicle stem cells (hfSC) having inactivated BMP signaling, which are discovered to express keratin 15. Also provided are hfSC that have constitutively activated BMP signaling and methods of using such hfSC for screening candidate agents suitable for inhibiting BMP signaling in hfSC and promoting hair growth. Further provided are methods of activating hfSC and promoting hair growth from hfSC. |
| 申请公布号 |
US2015033371(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
US201214344898 |
申请日期 |
2012.09.13 |
| 申请人 |
Kobielak Krzysztof;Kandyba Eve |
发明人 |
Kobielak Krzysztof;Kandyba Eve |
| 分类号 |
C12N5/071;A01K67/027;G01N33/50;A61K35/36 |
主分类号 |
C12N5/071 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated hair follicle stem cell (hfSC) that expresses keratin 15 (K15) and has decreased BMP signaling. |
| 地址 |
San Gabriel CA US |
