| 发明名称 |
PHAGE DISPLAY SYSTEM |
| 摘要 |
A phage display system is provided comprising a mutant phage-infected host cell adapted to express a peptide of interest fused to a phage capsid protein, wherein the mutant phage includes a nonsense mutation which prevents expression of the capsid protein as a functional protein, and wherein expression of the peptide of interest is controlled by an inducible repressor and by a suppressor that suppresses the nonsense mutation. |
| 申请公布号 |
US2015031583(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
US201414260732 |
申请日期 |
2014.04.24 |
| 申请人 |
Slavcev Roderick;Nicastro Jessica |
发明人 |
Slavcev Roderick;Nicastro Jessica |
| 分类号 |
C12N15/10;C12N7/00;C12N15/78;C12P21/00;C12N15/70;C12N15/74 |
主分类号 |
C12N15/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A phage display system comprising mutant phage-infected host cells adapted to express a peptide of interest fused to a phage capsid protein, wherein the mutant phage includes a nonsense mutation which prevents expression of the capsid protein as a functional protein, and wherein expression of the peptide of interest fused to the capsid protein is controlled by an inducible repressor and by a suppressor that suppresses the nonsense mutation. |
| 地址 |
Waterloo CA |
