Controlled Release Dosage Forms

摘要

The invention provides stable controlled release monolithic coating compositions for use in coating pharmaceutical oral dosage forms comprising a polyglycol having a melting point greater than 55° C. and an aqueous dispersion of a neutral ester copolymer lacking functional groups.

主权项

1. A stable controlled release monolithic coating composition for use in coating a pharmaceutical oral dosage form, said coating comprising:
a) an aqueous dispersion of a neutral ester copolymer without any functional groups; b) a poly glycol having a melting point greater than 55° C., and c) one or more pharmaceutically acceptable excipients;wherein said coating composition is coated onto said pharmaceutical oral dosage form and cured at a temperature at least equal to or greater than the melting point of said poly glycol.