| 发明名称 |
GENERATION OF PHOTORECEPTORS FROM HUMAN RETINAL PROGENITOR CELLS USING POLYCAPROLACTONE SUBSTRATES |
| 摘要 |
The present invention relates to biocompatible compositions for transplantation into a sub-retinal space of the human eye. The compositions include a biodegradable polyester film, preferably a polycaprolactone (PCL) film, and a layer of human retinal progenitor cells. The compositions of the invention can be used as scaffolds for the treatment a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration. |
| 申请公布号 |
US2015030658(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
US201314373881 |
申请日期 |
2013.01.22 |
| 申请人 |
THE SCHEPENS EYE RESEARCH INSTITUTE |
发明人 |
Regatieri Caio;Baranov Petr Y.;Young Michael J. |
| 分类号 |
A61K9/00;C12N5/0793;G01N33/50;A61L27/58;A61K9/70;A61L27/18;A61L27/34;A61L27/36;C12N5/0797;A61K35/30 |
主分类号 |
A61K9/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A biocompatible composition comprising:
a biodegradable and biocompatible polyester carrier film, and a layer of isolated human retinal progenitor cells and/or derivatives thereof adhered to at least a portion of the surface of said polyester film. |
| 地址 |
Boston MA US |
