| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES |
| 摘要 |
The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears). |
| 申请公布号 |
US2015030559(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
US201414508599 |
申请日期 |
2014.10.07 |
| 申请人 |
The Regents of the University of Michigan ;Phrixus Pharmaceuticals, Inc. |
发明人 |
Ng Rainer;Metzger Joseph M.;Reeve Lorraine;Markham Bruce |
| 分类号 |
A61K31/765;A61K45/06 |
主分类号 |
A61K31/765 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a poloxamer for use in treating, preventing or reducing diaphragm skeletal muscle injury or diaphragm skeletal muscle deficiency in a subject. |
| 地址 |
Ann Arbor MI US |
