The present invention relates to stable and high-producing site-specific integration (SSI) host cells, e. g. Chinese hamster ovary (CHO)-derived host cells, methods to produce and to use them.
申请公布号
EP2864489(A1)
申请公布日期
2015.04.29
申请号
EP20130729962
申请日期
2013.06.20
申请人
LONZA BIOLOGICS PLC.;PFIZER INC.
发明人
RANCE, JAMES;YOUNG, ROBERT;AGOSTINO, MICHAEL J.;MOFFAT, MARK;ZHANG, LIN;ZHANG, BAOHONG
