主权项 |
1. A compound of formula (I): or a metabolite, pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of one or more mTOR pathway related diseases, wherein, R1, R2 and R3 and R5 are each independently selected from H, alkyl, halogen, —CF3 or —CN; R4 and R6 are each independently selected from H, alkyl, halogen, alkoxy, —CF3, —OCF3, —SO2CF3, —SOCF3 or —SCF3; X is heteroatom, N(alkyl) or NH; and n is 1 to 20. |