URIDINE DIPHOSPHATE DERIVATIVES COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS

摘要

This disclosure relates to uridine diphosphate (UDP) derivatives compositions comprising therapeutically effective amounts of those UDP derivatives and methods of using those derivatives or compositions in treating disorders that are responsive to ligands such as agonists of P2Y6 receptor e.g. neuronal disorders including neurodegenerative disorders (e.g. Alzheimer s disease) and traumatic CNS injury as well as pain.