发明名称 |
BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE GATED SODIUM CHANNELS |
摘要 |
<p>abvDisclosed are compounds of Formula (A) or a salt thereof wherein 'Het' R and R are defined herein which have properties for blocking Na 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (A) or their salts and methods of treating neuropathic pain disorders using the same.</p> |
申请公布号 |
IN2959CHN2014(A) |
申请公布日期 |
2015.07.03 |
申请号 |
IN2014CH02959 |
申请日期 |
2014.04.17 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
LAYTON MARK E.;PERO JOSEPH E.;FIJI HANNAH;KELLY MICHAEL J. III;DE LEON PABLO;ROSSI MICHAEL A.;GILBERT KEVIN F.;ROECKER ANTHONY J.;ZHAO ZHIJIAN;MERCER SWATI PAL;WOLKENBERG SCOTT;MULHEARN JAMES;ZHAO LIANYUN;LI DANSU |
分类号 |
A61K31/423;C07D263/54 |
主分类号 |
A61K31/423 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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