发明名称 |
TEST FOR DIAGNOSING RESISTANCE TO AZACITIDINE |
摘要 |
<p>The invention relates to an analysis method for predicting resistance to azacitidine treatment in a patient using the BCL2L10 protein contained in a sample of biological fluid taken from said patient and also biological molecules which specifically bind the BCL2L10 protein. It is characterized in that a sample of biological fluid is recovered from a patient; the percentage of total cells in said biological fluid expressing the BCL2L10 protein is calculated; this calculated percentage is compared with a reference threshold value this threshold value being between 20% and 60%; and resistance to azacitidine treatment is diagnosed in a patient who has a percentage of cells expressing the BCL2L10 protein in said biological fluid which is greater than said reference value.</p> |
申请公布号 |
IN1795MUN2014(A) |
申请公布日期 |
2015.07.03 |
申请号 |
IN2014MU01795 |
申请日期 |
2014.09.11 |
申请人 |
UNIVERSITÉ NICE SOPHIA ANTIPOLIS;CENTRE HOSPITALIER UNIVERSITAIRE DE NICE;INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) |
发明人 |
CLUZEAU THOMAS;AUBERGER PATRICK;ROBERT GUILLAUME;LUCIANO FRÉDÉRIC |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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