| 发明名称 |
NON SYSTEMIC TGR5 AGONISTS |
| 摘要 |
<p>Compounds of structure (I) or a stereoisomer tautomer pharmaceutically acceptable salt or prodrug thereof wherein R R R R R R R R R A A X Y and Z are as defined herein. Uses of such compounds as TGR5 antagonists and for treatment of various indications including Type II diabetes meletus are also provided.</p> |
| 申请公布号 |
IN1433MUN2014(A) |
申请公布日期 |
2015.07.03 |
| 申请号 |
IN2014MU01433 |
申请日期 |
2014.07.15 |
| 申请人 |
ARDELYX INC. |
发明人 |
LEWIS JASON G.;REICH NICHOLAS;CHEN TAO;JACOBS JEFFREY W.;CHARMOT DOMINIQUE;NAVRE MARC;FINN PATRICIA;CARRERAS CHRISTOPHER;SPENCER ANDREW |
| 分类号 |
C07D241/42;C07D215/08;C07D265/30 |
主分类号 |
C07D241/42 |
| 代理机构 |
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