| 摘要 |
<p>THE PRESENT INVENTION PROVIDES PEPTIDES HAVING AN AMINO ACID SEQUENCE AS SET FORTH IN SEQ ID NO: SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 OR 288, AS WELL AS PEPTIDES HAVING THE ABOVE-MENTIONED AMINO ACID SEQUENCES IN WHICH 1, 2, OR SEVERAL (E.G., UP TO 5) AMINO ACIDS ARE SUBSTITUTED, DELETED, OR ADDED, PROVIDED THE PEPTIDES POSSESS CYTOTOXIC T CELL INDUCIBILITY. THE PRESENT INVENTION ALSO PROVIDES DRUGS FOR TREATING OR PREVENTING A DISEASE ASSOCIATED WITH OVER-EXPRESSION OF THE CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK AND/OR URLC10, E.G. CANCERS CONTAINING AS AN ACTIVE INGREDIENT ONE OR MORE OF THESE PEPTIDES. THE PEPTIDES OF THE PRESENT INVENTION FIND FURTHER UTILITY AS VACCINES.</p> |
