发明名称 |
METHOD FOR FUNCTIONALIZING A POROUS MEMBRANE COVERING OF AN OPTICAL SENSOR TO FACILITATE COUPLING OF AN ANTITHROMBOGENIC AGENT |
摘要 |
Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors. |
申请公布号 |
EP2760432(A4) |
申请公布日期 |
2015.09.30 |
申请号 |
EP20120835936 |
申请日期 |
2012.09.25 |
申请人 |
MEDTRONIC MINIMED, INC. |
发明人 |
SURI, JEFF, T.;PATTERSON, ERIC |
分类号 |
A61K9/00;A61L33/00;B05D3/00;G01N33/543 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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