发明名称 |
CHEMICALLY CLEAVABLE GROUP |
摘要 |
<p>Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactive components are a dienophile, particularly a trans-cyclooctene, and a diene, particularly a tetrazine.</p> |
申请公布号 |
EP2922574(A1) |
申请公布日期 |
2015.09.30 |
申请号 |
EP20130802460 |
申请日期 |
2013.11.22 |
申请人 |
TAGWORKS PHARMACEUTICALS B.V. |
发明人 |
ROBILLARD, MARC STEFAN;VERSTEEGEN, RONNY MATHIEU;TEN HOEVE, WOLTER;ROSSIN, RAFFAELLA |
分类号 |
A61K47/48;C07C13/00 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|