发明名称 |
SYSTEMS AND DEVICES FOR MODULATING AUTONOMIC TONE |
摘要 |
Various embodiments intermittently deliver a sympathetic stimulus, including deliver a sequence of stress-inducing pacing pulses adapted to increase sympathetic tone during the stress-inducing pacing. The stress-inducing pacing results in a parasympathetic reflex after the sequence of stress-inducing pacing. The embodiment further delivers neural stimulation to elicit a parasympathetic response or a sympathetic response in a coordinated manner with respect to the sequence of stress-inducing pacing pulses. The neural stimulation is timed to elicit the parasympathetic response after the sequence of stress-inducing pacing pulses and concurrent with at least a portion of the parasympathetic reflex to the sequence of stress-inducing pacing to enhance a parasympathetic effect of the parasympathetic reflex, or to elicit the sympathetic response during the sequence of stress-inducing pulses to provide a larger sympathetic stimulus, resulting in an enhanced parasympathetic reflex in response to the large sympathetic stimulus. |
申请公布号 |
EP2268355(B1) |
申请公布日期 |
2015.09.30 |
申请号 |
EP20090720923 |
申请日期 |
2009.03.04 |
申请人 |
CARDIAC PACEMAKERS, INC. |
发明人 |
SHUROS, ALLAN, C.;ARCOT-KRISHNAMURTHY, SHANTHA;KENKNIGHT, BRUCE, H.;DAUM, DOUGLAS, R. |
分类号 |
A61N1/362;A61N1/36 |
主分类号 |
A61N1/362 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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