发明名称 FULLY HUMANIZED ANTI-HER2 ANTIBODY, PREPARATION METHOD AND USE THEREOF
摘要 <p>The invention provides a fully human anti-HER2 monoclonal antibody, which has an amino acid sequence of heavy chain variable region as shown in SEQ ID NO : 6 and an amino acid sequence of light chain variable region as shown in SEQ ID NO :8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.</p>
申请公布号 EP2540745(B1) 申请公布日期 2015.09.30
申请号 EP20100846324 申请日期 2010.04.16
申请人 SHANGHAI BIOMABS PHARMACEUTICALS CO., LTD 发明人 LI, CHUAN;TONG, XIN;KAN, YING
分类号 C07K16/28;A61K39/00;A61P35/00;C07K16/30;C07K16/32;C12N15/13;C12N15/63 主分类号 C07K16/28
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