| 发明名称 | Cyclic pentadepsipeptides and microorganism of <i>Fusarium </i>strain producing the same | ||
| 摘要 | Disclosed is a Fusarium strain producing novel cyclic pentadepsipeptides which are of excellent multidrug resistance-reversing activity and inhibitory activity against cancer cells. Also, novel cyclic pentadepsipeptides are provided as active ingredients of the compositions useful in the treatment of cancer and diseases associated with multidrug resistance. | ||
| 申请公布号 | US9145442(B2) | 申请公布日期 | 2015.09.29 |
| 申请号 | US201414502520 | 申请日期 | 2014.09.30 |
| 申请人 | Chung-Ang University Industry-Academy Cooperation Foundation | 发明人 | Lee Chan;Song Hyuk-Hwan;Lee Hee-Seok |
| 分类号 | A61K38/12;C07K5/00;C07K7/00;C07K16/00;C07K17/00;C07K11/02;C12P21/02;C12R1/77;A61K38/15;A61K38/00 | 主分类号 | A61K38/12 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Kim Kongsik |
| 主权项 | 1. A method for preventing or treating a cancer disease in a subject in need thereof, said method comprising administering to the subject a pharmaceutical composition comprising an effective amount of an isolated cyclic pentadepsipeptide of the following Chemical Formula I or an isolated cyclic pentadepsipeptide of the following Chemical Formula II: | ||
| 地址 | Seoul KR | ||