发明名称 |
LOW CONCENTRATION ANTIBODY FORMULATIONS |
摘要 |
The present invention is directed formulations for low concentrations of therapeutic proteins and methods of making the same. In one aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) a surfactant; wherein the molar ratio of surfactant to therapeutic protein is at least 100. In another aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) an antioxidant, wherein the molar ratio of antioxidant to therapeutic protein is at least 750. |
申请公布号 |
SG11201506499Y(A) |
申请公布日期 |
2015.09.29 |
申请号 |
SG11201506499Y |
申请日期 |
2014.03.13 |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED |
发明人 |
CROTTS, GEORGE;MORAR-MITRICA, SORINA |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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