| 发明名称 |
STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS |
| 摘要 |
<p>The invention relates to the therapeutic use of novel stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides novel RNA-based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.</p> |
| 申请公布号 |
CA2692161(C) |
申请公布日期 |
2015.09.29 |
| 申请号 |
CA20082692161 |
申请日期 |
2008.07.07 |
| 申请人 |
IDERA PHARMACEUTICALS, INC. |
发明人 |
KANDIMALLA, EKAMBAR R.;LAN, TAO;WANG, DAQING;BHAGAT, LAKSHMI;AGRAWAL, SUDHIR |
| 分类号 |
C12N15/117;A61K31/7105;A61K31/7125;A61K39/00;A61K39/39;A61K39/395;A61P37/02;C07H21/02 |
主分类号 |
C12N15/117 |
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