| 摘要 |
Compositions, kits, and methods for repairing bonds, for example, disulfide bonds, in hair or on the skin are disclosed. The compositions provide improved conditioning benefit for dry hair or moisturize the skin. The compositions also provide a long lasting moisturized feel and smooth feel to the skin or hair, without feeling greasy. The compositions contain one or more compounds that covalently bind at least two thiol groups in the hair or on the skin. Use of the binding compositions prevents reversion of the repaired bonds to their free thiol state, for at least one week or one month, or more, after a single application of the composition. Improved methods of styling hair, for example permanent hair waving, hair curling, hair coloring or highlighting, and hair straightening, are also provided. |
| 主权项 |
1. A kit comprising:
(a) a first formulation capable of reducing disulfide bonds in hair to produce free thiol groups, and (b) a second formulation comprising a binding agent of Formula I wherein A, B, C, and D are reactive moieties capable of reacting with the free thiol groups and contain one or more charges, and wherein each of A, B, C, and D independently contains a moiety selected from the group consisting of a vinyl sulfone, an acrylate, a methacrylate, a styrene group, an acryl amide group, a methacryl amide group, a maleate group, a fumarate group, and an itaconate group; R is a linker that contains two or more charges, wherein the charges are opposite to the charges on the reactive moieties, wherein n=1-10, and wherein R is not a polymer, and wherein the sum of the charges is zero; and wherein the reactive moieties are ionically bound to the linker; wherein each occurrence of p, q, r, and s is independently an integer from 0 to 25, and wherein the sum of p+q+r+s is equal to or greater than 2 in an effective amount to covalently bind free thiol groups in hair. |
